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Lm PC-PLC C143S and Lm PC-PLC C168S , or a double cysteine substitution, i.e
Although this work suggested a role for S-layer in C
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nevertheless, data on AD seem controversial since a large study and a Mendelian randomization revealed a causal association between genetically elevated CRP and reduced risk for AD, while another study reported that genetically predicted increased CRP may be a causal risk for AD [578,579,580]
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