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Description
A phase I study of cabozantinib (XL184) in patients with renal cell cancer

This is related to the copper component
R., Stanford K

In 2016, researchers first designed phosphate and pyrophosphate-containing linkers coupled with the well-established, cathepsin B sensitive, Val-Cit-PABA moiety aiming to deliver glucocorticoids

Aromatic amino acids were provided to circumvent the inactivating effect of H 2 O 2 upon the aromatic biosynthetic pathway (Sobota et al., 2014)
