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The so-called myokines, produced by the myocytes and released by muscle contraction during physical exercise, have autocrine, paracrine, and endocrine functions, and help perform the regulation of the immunometabolism thanks to their ability to induce significant metabolic, energetic and hormonal changes (Pillon et al., 2013

Proposed studies utilizing rat models incorporate prevention of secondary insults post-TBI with a glutathione mimetic

For Persistent Fatigue : Amino Acid Complexes: These building blocks of protein support muscle recovery and energy production

10.1371/journal.pone.0086686 70 SaagaM.MosiskaP