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Abstract Vitamin C deficiency, one of the oldest-known nutritional disorders, is now uncommon in high-income countries

Yang, Y., Xu, J., Zhou, J., Xue, J., Gao, J., Li, X., Sun, B., Yang, B., Liu, Z., Zhao, Z., Luo, Q., Zeng, Q., Zheng, L., & Xiong, C
RCTs reporting on the use of vitamin C in conjunction with other therapies were excluded

Furthermore, FSP1, known as apoptosis inducing factor mitochondria associated 2 gene (AIFM2), is a new limiting factor in ferroptosis by reducing the expression of CoQ10 (Doll et al., 2019)

(8) Constipation was defined according to the Rome III criteria
