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Rodriguez C, Mayo JC, Sainz RM, Antoln I, Herrera F, Martn V, et al

The structure of the complex shows that the enzyme uses several highly conserved residues, e.g., D179, H413, N489, W619, N636, and K638, to form hydrogen bonds and electrostatic interactions with the glucuronic acid moiety of the substrate

Dhodh inhibitors sensitize to ferroptosis by fsp1 inhibition

42 They can migrate to specific injury sites and differentiate into multiple cells and tissues, such as glial cells, neurons, or chondrogenic tissues

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