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A recent study has implicated an effect of LA on MLC through inhibition of pMLC (47)
27 investigated five patients with clEDS and histological investigations reported gross abnormalities of the elastic fibers and microfibrils in the dermis of these patients and reduced dermal collagen content

Site rotation: Move between abdomen, thighs and upper arms to reduce local irritation and prevent lipoatrophy [9]

Rasmussen et al., 2016)

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