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The MDH2 catalyzes the reversible oxidation of malate to oxaloacetate using NAD+/NADH as a cofactor in the citric acid cycle (45)

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It is also essential for the growth and development of red blood cells, which is why it is used to treat anemia

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The pathogenic side of LL-37 in lupus In lupus patients, LL-37 has been found to form complexes with self-DNA released from dying cells

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