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And retatrutide, a triple agonist targeting GLP-1, GIP, and glucagon receptors simultaneously, achieved up to 24% weight loss in early trials

The survival and activation/proliferation of OPCs, as well as and their enhanced and continuous differentiation into Enpp6 -positive newly-forming/formed OLs, despite the late onset (from 2-3 weeks and beyond) demyelination under the continuous pressure of CPZ, underpinned a strong potential for remyelination after CPZ withdrawal

L., Schnoor, M