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Introduction The term oxidative stress (OS) applies when increased amounts of reactive oxygen species (ROS) surpass the antioxidant (AOX) capacity that naturally offers the protective balance ( Hence, AOX therapy to enhance fertility by protecting against the harmful effects of ROS is theoretically feasible

Besides these antioxidant defenses that ensure H 2 O 2 elimination, aquaporins have been shown to modulate mitochondrial ROS generation

Kratz F, Drevs J, Bing G, Stockmar C, Scheuermann K, Lazar P, Unger C: Development and in vitro efficacy of novel MMP2 and MMP9 specific doxorubicin albumin conjugates

They found that at the dose of 0.2% for 6 weeks, CPZ could induce complete demyelination in the corpus callosum while having no detectable toxic effect on the peripheral organs such as the liver and causing only mild weight loss in the mice

10.3390/molecules28104085 10.3390/molecules28104085 [DOI] [PMC free article] [PubMed] [Google Scholar] Gabdoulline RR, Kummer U, Olsen LF, Wade RC (2003) Concerted simulations reveal how peroxidase compound III formation results in cellular oscillations