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These mice survived for a total of 25 days and naturally died, which we defined as the survival endpoint as illustrated in Fig

10.1007/978-90-481-2259-2_24 Adv

If is continuous and its concavity changes either from up to down or down to up at , then has an inflection point at

doi: 10.2478/rir-2022-0020 209 AguirreJHansbergWNavarroR

At the TME level, stress factors such as hypoxia, acidosis, and nutrient deprivation persistently activate the UPR, while ERS, in turn, remodels the TME [102, 103]
