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Specifically for NAC, the reduction in mortality (odds ratio 0.56, 95 % confidence interval 0.470.67) remained significant in a multivariate analysis adjusted for baseline characteristics and concomitant use of corticosteroids

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Increased NADH lead to depletion of aspartate (Asp) production, and consequently asparagine (Asn) as well since Asp serves as a predominant precursor for the generation of Asn

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