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doi: 10.1074/jbc.273.50.33811
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Soluble A oligomers, pathological tau, and neuroinflammatory mediators disrupt synaptic plasticity, impair neurotransmission, and alter dendritic spine architecture long before extensive neuronal loss occurs
While rare, potential symptoms may include nausea, vomiting, and diarrhea
Meaningful GLP-1 receptor activation for appetite suppression typically begins around 0.5mg to 1.0mg, though individual responses vary
