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Decrease in vitamin C concentration in human lenses during cataract progression

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The purpose of this pilot study was to explore whether nitisinone is safe and whether we could pick up a signal that the drug works. Oculocutaneous albinism (OCA) is a rare inherited disease caused by mutations in genes needed to make melanin, a dark-colored pigment found in hair, skin, and eyes

After being thoroughly briefed on the study's objectives, procedures, and potential risks, all participants were informed and consented