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According to the predicted function of proteins encoded by the LHR, the genomic island may thus contribute to the turnover of misfolded or aggregated proteins, the osmotic stress response, and mitigate oxidative stress (Mercer et al., 2015)

PMID: 41747719 Int J Biol Sci 2022 Jan 1;18(2):717-730

Peptides are more targeted and typically considered safer, as they work more subtly by signaling specific cellular responses, whereas steroids can cause more systemic and potentially disruptive changes to the body's hormone and metabolic processes

(2005) ADAM12: the long and short of it

Morawietz G, Ruehl-Fehlert C, Kittel B, Bube A, Keane K, Halm S, et al