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Its given under a doctors watch, with special rules for how its mixed and given

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You should contact a doctor or seek emergency care if you experience: Difficulty breathing or swallowing Significant facial or throat swelling Persistent or worsening injection-site reactions (such as increasing pain, pus, or red streaks) Severe, unusual, or unexpected symptoms after use Signs of systemic illness like extreme fatigue, jaundice (yellowing of the skin or eyes), or neurological changes, which could indicate severe copper imbalance

Studies showed people with combined deficiencies felt less fatigue when both vitamins were corrected instead of just one

A., Makrantonaki, E., & Zouboulis, C