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The liver plays a key role in maintaining blood glucose homeostasis during both fasting and postprandial periods 3,4,5,6

Glutathione S-transferases are a family of enzymes that facilitate glutathiones redox maintenance function by conjugating glutathione onto oxidative substrates, thereby masking their reactivity and enhancing their secretion (Townsend et al,

However, the impact of other physiologically relevant metal ions on the anticancer activity and acquired resistance profile of thiosemicarbazones remains largely unknown(Ding and Lind 2009)

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A previous review on OOT for knee OA reinforced this finding, suggesting that while short to medium-term results were encouraging, the included RCTs exhibited discernible methodological constraints [8]