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Yap5 is an iron-responsive transcriptional activator that regulates vacuolar iron storage in yeast

The exploration of macrocycles for drug discoveryan underexploited structural class

However, these preventive studies confirmed that VIP was capable of reducing DSS associated colitis and showed benefit in this model, which resembles human UC

10.1523/jneurosci.20-01-00326.2000 [DOI] [PMC free article] [PubMed] [Google Scholar] Ohnishi H., Mizuno S., Nakamura T
S/P/G/M (succinate, pyruvate, glutamate, malate respectively)
