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B., Peterson, D., & Royse, D

In our view, the implementation of this treatment paradigm could provide benefit to many cancer patients
doi: 10.1007/s004010050490

The therapeutic regimen of the BRAF inhibitor dabrafenib combined with the downstream MEK inhibitor trametinib for NSCLC with metastatic BRAF V600e mutation has been approved by the FDA and European Medicines Agency (EMA) [33]
The nanocapsules successfully prevented cytotoxicity in keratinocytes, reduced ear thickness in mice, and decreased MPO activity, as well as IL-6 and KC (CXCL 1) concentrations, suggesting the potential of eugenol as a bioactive molecule for improved skin permeation and irritation prevention [79]
