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Changes to the microbial phyla and genera observed in the 5A-1MQ-treated group switched from WD to LD could have been driven by additive, synergistic, or independent mechanisms relative to those induced by diet switch alone, which could not be determined with the current study design that lacked a group treated with 5A-1MQ and maintained on WD

This supports use of AOD 9604 as a controlled research tool when isolating lipolytic mechanisms from broader GH effects

Fortin JL, Baud FJ, Astier A, Barriot P, Lecarpentier Y

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