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Mice in the GHK-Cu group had an enhanced performance on special memory tests and learning navigation tasks and demonstrated decreased neuroinflammation and axonal damage markers as compared to the placebo group

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The results revealed that Neuroactive ligand-receptor interaction and Calcium signaling pathway were the primary mechanisms through which this combination exerted synergistic effects

Different forms of cobalamin exist with linkages of methyl, adenosyl or hydroxo groups to cobalt, resulting in methylcobalamin, adenosylcobalamin and hydroxocobalamin, respectively