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Description
The PI3K/Akt pathway activated by IGF1R is a major anti-apoptotic pathway in neurons, which drives interest in IGF1R agonism as a potential neuroprotective strategy in preclinical research

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Combined with your medical history, biomarkers, and real-time symptom feedback, these predispositions help your provider tailor your dose escalation, monitor for specific adverse events, and decide whether tirzepatide or an alternative GLP-1 option suits your individual needs

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BACKGROUND FDA Circular No
