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Our later studies on the Shank3 -/- and Cntnap2 -/- knockout mice, the human SH-SY5Y cell line, and the human induced pluripotent stem cellsderived cortical neurons isolated from patients carrying a SHANK3 mutation confirmed the increased levels of NO and protein SNO [172,173,174,175,176]

Additionally, case reports and small-scale studies have suggested potential benefits of IV glutathione in multiple sclerosis, Alzheimer's disease, and stroke recovery

Topiramate does not affect the acquisition or expression of ethanol conditioned place preference in DBA/2J or C57BL/6J mice