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The oxindole scaffold, possessing increased degrees of freedom, exhibited more pronounced conformational changes upon stereochemical inversion, which correlated with larger swings in affinity (Figure 10)
Packer, L.) 121126 (Academic Press, New York, New York, 1984)
Sies H, Koch OR, Martino E, Boveris A: Increased biliary glutathione disulfide release in chronically ethanol-treated rats
Investigators have reported improving the stability of SLNs, drug loading capacity, and targeting capabilities
