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Hypothesis 4: The cardiometabolic reaction to dietary changes in thyroid function differs by sex, exhibiting varied effects in male and female individuals with autoimmune thyroid diseases

Recent studies reveal that peroxisomes and mitochondria form specialized membrane contact sites mediated by acyl-coenzyme A-binding domain-containing protein 5 (ACBD5) and protein tyrosine phosphatase interacting protein 51 (PTPIP51), through which peroxisomes alleviate mitochondrial oxidative stress by importing excess ROS [205]