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Description
During oocyte meiosis, coordinated Ca 2+ release from the ER to mitochondria through the MAMs region is essential for Ca 2+ oscillations, which serve as key signals for cytoplasmic maturation, spindle reorganization, and chromosome alignment [64, 65]

I.u, & Shlyshalova, N
Phosphorylated c-Jun, in turn, regulates biological processes such as cell proliferation and apoptosis [59]

And frankly, if diabetes is an issue, that is absolute top priority to fix ASAP, because that is arguably the single strongest predictor of early cataract development
kidney or liver disease