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8 Conclusion This review summarizes the current evidence on the multifaceted role of TMAO in regulating immunometabolism during IBD
It has been suggested that the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway is involved in the induction of HO-1 expression by acetylcarnitine [18]
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The increase in TMAO was modest as the authors suggest but in five subjects TMAO production could be suppressed by giving oral broad-spectrum antibiotics, suggesting how intestinal microbiota contribute to the link between red meat consumption and CVD risk [86]
