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Brain Behavior, and Immunity , 44 , 18

Specifically, the HFD condition was associated with a reduction in the expression levels of 4E-BP1, S6K1, and mTOR genes, whereas the combined interventions were found to elevate the levels of 4E-BP1, S6K1, and IGF-1, in addition to enhancing muscle fiber diameter ( n = 11, age 25 1 years), older sedentary individuals ( n = 9, age 64 2 years), and older endurance-trained males ( n = 9, age 64 2 years)

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Studies done in the elderly showed parallel results in terms of muscle output and endurance

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