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EGCG enhances gap junctional communication between the adjacent cells and thus protects the cells from tumor development, as tumor promoters inhibit gap junctional intercellular communication and isolate preneoplastic cells from the regulatory influence of surrounding cells, considered to be a key mechanism of tumor promotion [203]
However, dermatologists and nutrition experts increasingly emphasise that absorption matters more than dosage when it comes to supplements
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Shi J, et al
Remarkably, both human and mouse hepatocytes enlist these cell-autonomous immune programs to eliminate Plasmodium, with their pharmacologic or genetic inhibition leading to profound malarial susceptibility in vivo
