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doi: 10.1038/nature03121 [DOI] [PubMed] [Google Scholar] 213
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In March 2026, the company submitted a protocol amendment to Swissmedic and the Swiss Ethics Committee that lowered the drug-to-tumor volume ratio and reduced dosing to a single injection of INT230-6, changes that supported the current restart

Weight loss, HbA1c reduction, and tolerability of cetilistat in a randomized, placebo-controlled phase 2 trial in obese diabetics comparison with orlistat (Xenical) Obesity (Silver Spring) 2010;18(1 ): 10815

menstruating women, especially those with heavy periods
