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A poor intestine absorption caused by infection, inflammation or a pathology in the intestine morphology may cause an adverse Ca 2+ balance[4], which under chronic conditions leads to a deleterious bone mineralization

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These data demonstrate that GGCT enzymatically diverts Gln flux away from the TCA cycle, preferentially shunting Gln toward GSH synthesis to sustain redox homeostasis

Some mycotoxins have been related to this condition: According to Sokolovi et al

The authors noted that well-designed, adequately powered clinical trials were lacking, and that definitive efficacy claims could not be supported by the existing literature at the time of publication