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Proper handling is paramount for valid research

Benefit: Reduces wrinkles, fine lines, and promotes youthful skin
doi: 10.1136/bcr.09.2008.0950 100 ConeCJBachyryczAMMurataGH

While this reaction is entirely normal, it can cause mild discomfort for a few days

Plus to physical symptoms, many individuals experience trouble sleeping, ongoing fatigue, and mood disturbances such as depression or generalized anxiety disorder