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Demonstration of bioequivalence of different formulations is not assumed to be significantly influenced by characteristics of the study population

doi: 10.1016/0196-9781(88)90216-1

So less fat, more of your testosterone in men stays as testosterone and wont convert to estrogen. Over time, some men may even be able to wean off TRT under medical supervision, says Kohn

10.1002/phar.1890 137 FournierE.LevequeM.RuizP.RatelJ.DurifC.ChalanconS.et al

And where lifestyle alone may not be enough, we can support the system : with precursors like NAC and glycine and, in modern settings, with clinical delivery methods that restore what diabetes so often drains