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Disclosure of interest: Nothing to disclose Poster Session II - RECOVERY, REHABILITATION AND OUTCOME 03.00 - RECOVERY, REHABILITATION AND OUTCOME - 03.03 - PROGNOSIS AND OUTCOME AFTER STROKE P833 - ESOC25-1627 POST-STROKE COGNITIVE IMPAIRMENT AND CEREBROVASCULAR HEMODYNAMICS Manuel Martnez-Marino 1 , Megan Cerda-Mancillas 2 , Moses Guerrero-Toledo 3 , Victor Carrasco Wall 4 , Fernando Flores-Silva 3,5 , Carlos Cant-Brito 3,5 , Miguel Garcia-Grimshaw 3,5 , Alberto Hidalgo-Bravo 3 , Erwin Chiquete 3,5 , David Vidal-Gonzalez 3 1 UAdeC, Universitary Hospital of Saltillo, UNAM, Saltillo, Coahula, Mexico, 2 IMSS, UNAM, Saltillo, Coahula, Mexico, 3 UNAM, Mexico, Mexico, 4 University of Alberta, Alberta, Canada, 5 Instituto Nacional de Ciencias Mdicas y Nutricin Salvador Zubiran, Mexico, Mexico Background and Aims: Post-stroke cognitive impairment (PSCI) occurs in 50% of stroke survivors, with decrease quality of life

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Neuropeptide research positions DSIP alongside Selank for GABAergic anxiolytic studies and Pinealon for pineal gland-derived bioregulatory mechanisms affecting sleep-wake cycles

Salahdine F, Han T, Zhang N