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Description
Azeliragon (TTP488), an orallyadministered smallmolecule antagonist of the RAGE, can effectively traverse the bloodbrain barrier
Three out of 86 minor adverse events experienced were noted to be probably related to the infusion
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L-2-oxothiazolidine-4-carboxylic acid (OTC) treatment attenuated plasma and tissue P-selectin levels, suggesting that the upregulation of P-selectin in hyperhomocysteinemic mice is also regulated by redox mechanisms [61]
