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a proportion of patients with Parkinson's disease develop dementia Cognitive impairment also occurs in the Parkinson-plus syndromes of progressive supranuclear palsy and corticobasal degeneration (and the same underlying pathology may cause the clinical syndromes of frontotemporal lobar degeneration)

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Notably, a recent study has shown that peroxisomes play a direct role in maintaining mitochondrial redox homeostasis through contactmediated ROS transfer