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Because we previously reported that old C57BL/6J mice and older adults share many age-associated abnormalities [14,22,64], these mice were an ideal to conduct our investigation of cognitive decline and brain abnormalities in aging

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Under hepatitis B virus (HBV) infection in vitro and in vivo, sulforaphane promotes macrophages to the pro-inflammatory M1 phenotype [374], while, under inflammatory conditions both in vitro and in vivo, it induces macrophages to change to the anti-inflammatory M2 phenotype [375], as explained in the various sections of this article

Enzymes like superoxide dismutase, catalase, and glutathione peroxidase play a significant role in neutralizing harmful reactive species

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