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Food and Chemical Toxicology, 62 , 869875

ACTL6A knockdown (KD) via short hairpin RNA (shRNA) transfection exerted a marked negative effect on GC cell proliferation, while overexpression of ACTL6A exerted a positive effect on GC cell proliferation (Fig

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In the nucleus, STAT3 dimers bind to specific DNA sequences, known as STAT response elements (SREs), in the promoter regions of target genes, binding of STAT3 to SREs leads to the transcriptional activation of target genes, including those involved in immune responses, cell proliferation, survival, and inflammation [4]

[DOI] [PubMed] [Google Scholar] 61.Askari M., Daneshzad E., Darooghegi Mofrad M., Bellissimo N., Suitor K., Azadbakht L