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Biofactors 6, 321338

MOTS-c is a mitochondrial-derived peptide that regulates metabolic pathways and helps with the proper utilization of fatty acids for energy

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Associated hearing loss occurs, particularly with otologic diseases (including Meniere syndrome), meningitis, and autoimmune disease (including Cogan syndrome) (160), but hearing can be normal in these conditions, even in the presence of significant bilateral vestibulopathy (01)

The emergence of resistance to long-term treatment of melanoma with v-RAF murine sarcoma viral oncogene homolog B1 (BRAF) inhibitors and the related cellular dedifferentiation enhances the vulnerability of cells to various ferroptosis inducers