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Raychaudhuri SS, Pramanick P, Talukder P, Basak A (2021) Chapter 6polyamines, metallothioneins, and phytochelatinsnatural defense of plants to mitigate heavy metals

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Aside from direct effects on principal neurons, a second, hypothesized mechanism for ketamines antidepressant effect is an indirect impact on principal excitatory neurons via inhibition of fast spiking PV-positive interneurons resulting in cortical disinhibition [171,172,173]

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