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Clinical trials of inflammasome inhibitors further validate the therapeutic potential of innate immune pathway modulation

Celiac disease (CD) is an autoimmune disorder affecting 1% of the population, causing reversible inflammation of the small intestine mucosa and accompanied by acute symptoms such as diarrhea, constipation, bloating, nausea, and vomiting

Li and colleagues fabricated biomimetic fiber matrices with distinct architectures and showed that aligned nanofibers markedly increased directional migration and migratory persistence of tumor cells ( Notably, these topography-driven migration effects intersect with EMT plasticity

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