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Serpin-mediated NSP inhibition is unique in that after the initial formation of a non-covalent and reversible serpin-protease complex, two pathways can occur (87)

A proportion of pre-malignant lesions are present as either leucoplakia (white patches) or erythroplakia (red patches) which can progress to advanced stage of HNSCC

After that, bacterial contamination becomes more likely even with refrigeration

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Factors such as age, overall health, and any pre-existing medical conditions may impact whether or not IV drip therapy is recommended