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Most concluded that the substance appears quite promising, but that there are too many unknowns to justify its clinical use at this time

10.1038/mtm.2015.43 [DOI] [PMC free article] [PubMed] [Google Scholar] Song H., Yang P., Huang P., Zhang C., Kong D., Wang W

Evidence suggests that combination therapy integrating lifestyle modifications with pharmacological interventions yields superior metabolic outcomes compared to monotherapy, demonstrating significant improvements across multiple metabolic parameters and associated comorbidities

Several cellular processes are involved in the pathogenesis of AIH, including liver metabolism, mitochondrial oxidative stress and dysfunction, sterile inflammation, endoplasmic reticulum stress, autophagy, and microcirculation dysfunction