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The pathogenesis of T2-high and T2-low asthma is illustrated in Figure 2

10.1038/aps.2017.5 284 ZouY.PalteM

O 2 reactivity and diffusion capacity can be increased if it can be protonated to form its conjugated acid, perhydroxyl radical (HO 2 ) (De Grey, 2 has a pKa of ~4.88 most of the O 2 will exist in the deprotonated state (~0.3% of O 2 exists as HO 2 ) (De Grey, 2013)

Both GLP-1 and GH peptides affect glucose metabolism, requiring monitoring

[DOI] [PMC free article] [PubMed] [Google Scholar] 34.Lammers KM, Lu R, Brownley J, Lu B, Gerard C, Thomas K, Rallabhandi P, Shea-Donohue T, Tamiz A, Alkan S, Netzel-Arnett S, Antalis T, Vogel SN, Fasano A