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Targeting proximal tubule mitochondrial dysfunction attenuates the renal disease of methylmalonic acidemia
Most peptides degrade rapidly in the stomach and intestines, so oral preparations typically provide negligible systemic availability, generally less than 2%
Bjelakovic et al
GHK-Cu occurs naturally in human plasma at approximately 200 ng/mL at age 20, declining to about 80 ng/mL by age 60
