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Steroid 5-reductase as a novel therapeutic target for schizophrenia and other neuropsychiatric disorders.Curr

In yeast, Ohsumis and Klionskys laboratories first identified that ATG32 acts as the mitophagy-specific receptor, which directly interacts with the selective autophagy adaptor ATG8 via an ATG8-interacting motif (AIM) and ATG11 to form the nascent autophagosome (Kanki et al., 2009

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Additionally, it reduced trimethylamine levels and the relative abundance of Helicobacter while boosting beneficial groups like Ruminococcus and Lachnospiraceae