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Animal studies show substantial evidence across stroke models (full functional recovery in spatial memory, motor coordination, balance), Parkinsons models (protection of dopaminergic neurons, near-complete prevention of mortality), multiple sclerosis models (significantly less brain damage), and traumatic brain injury (reduced hemorrhage and edema)

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By selectively inhibiting NNMT, researchers use 5-Amino-1MQ to investigate pathways involved in cellular function, enzyme activity, and biochemical signaling

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Journal of biological regulators and homeostatic agents