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Zepbound holds FDA approval for chronic weight management and is delivered by injection, with no oral version of tirzepatide currently available for either the diabetes or weight-loss indication

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For randomised clinical trials, the Jadad scale ( To complement the Jadad score, the Cochrane Risk of Bias Tool (RoB 2) ( For observational studies (cohort and case-control), the NewcastleOttawa Scale (NOS) ( Risk of bias was interpreted as follows: i) Low risk: All criteria met or no more than one rated as unclear

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