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doi: 10.1016/j.ophtha.2022.05.021

Hamed SA

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The fraction of Lcarnitine excreted unchanged in urine was 0.730.95, suggesting that although renal reabsorption of Lcarnitine is very efficient at physiological concentrations, renal transporters become saturated at the high concentrations achieved with IV dosing resulting in extensive renal excretion