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Discussion In summary, our findings uncover a previously unknown link between the ER resident and UPR sensor protein IRE1 and ferroptosis regulation independent of UPR activation and IRE1s canonical downstream effector XBP1

We next wanted to investigate the contributions of IMSlocalized redox processes to E GSH [IMS] including the respiratory chain, antioxidative systems and the Erv1Mia40 machinery for protein oxidation (Figure 5C)

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T cell subsets and functions in atherosclerosis
