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Prognostic and therapeutic opportunities Prognosis A current limitation of many of the functional studies discussed in this review is that they are generally based only on cell biology experimentation, in some cases with pre-clinical confirmation in vivo

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Investigations of oxidative PTMs (ox-PTMs) that occur in vitro or in vivo are currently being performed with focused redox proteomics techniques (299301)

Taken together, these findings extend the H 2 O 2 -decomposing activity of KDS12025 beyond the brain, illustrating its capacity to target systemic inflammation-associated oxidative stress and highlighting its potential as a broad-spectrum therapeutic for diverse H 2 O 2 -driven diseases

Overexpression of pulmonary extracellular superoxide dismutase attenuates endotoxin induced acute lung injury